Simprot : Simprot v1.0 is a program that simulates protein evolution by substitution, insertion and deletion. It is based on the paper

Pang, A, Smith A, Nuin PAS, and Tillier, ERM 2005. Simprot: using an empirically determine indel distribution in simulations of protein evolution. BMC Bionformatics 6:236.

Simprot v1.0 was born as a command line tool for Linux and now has been developed for different systems. A new graphical version for Linux and Windows has been released. Also a web interface is available to run the simulations, having the same functionality of the standalone programs.

At the moment Simprot can be obtained only at Elisabeth Tillier's site.